:root {
  --bg: #0a0e17;
  --bg-elevated: #111827;
  --bg-card: #161d2e;
  --fg: #e8edf5;
  --fg-muted: #8b95a8;
  --accent: #3b82f6;
  --accent-glow: rgba(59, 130, 246, 0.15);
  --accent-bright: #60a5fa;
  --border: rgba(139, 149, 168, 0.12);
  --hema: #ef4444;
  --card: #f97316;
  --hepa: #eab308;
  --pulm: #22c55e;
  --neur: #8b5cf6;
  --onco: #ec4899;
  --hcp: #06b6d4;
  --font-display: 'Space Grotesk', sans-serif;
  --font-body: 'DM Sans', sans-serif;
  --max-width: 1120px;
}

* { margin: 0; padding: 0; box-sizing: border-box; }

body {
  background: var(--bg);
  color: var(--fg);
  font-family: var(--font-body);
  font-size: 17px;
  line-height: 1.65;
  -webkit-font-smoothing: antialiased;
}

h1, h2, h3, h4 {
  font-family: var(--font-display);
  font-weight: 600;
  line-height: 1.2;
}

.section-container {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 0 24px;
}

/* ─── HERO ─── */
.hero {
  padding: 100px 24px 60px;
  max-width: var(--max-width);
  margin: 0 auto;
}

.hero-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 60px;
  align-items: center;
  margin-bottom: 48px;
}

.hero-tag {
  display: inline-block;
  font-family: var(--font-display);
  font-size: 13px;
  font-weight: 500;
  letter-spacing: 0.08em;
  text-transform: uppercase;
  color: var(--accent-bright);
  background: var(--accent-glow);
  padding: 6px 14px;
  border-radius: 4px;
  margin-bottom: 24px;
}

.hero h1 {
  font-size: clamp(2.4rem, 5vw, 3.6rem);
  color: var(--fg);
  margin-bottom: 24px;
}

.hero h1 .accent {
  color: var(--accent-bright);
}

.lede {
  font-size: 1.15rem;
  color: var(--fg-muted);
  max-width: 520px;
  line-height: 1.7;
}

.hero-stats {
  display: flex;
  flex-direction: column;
  gap: 16px;
}

.stat-card {
  background: var(--bg-card);
  border: 1px solid var(--border);
  border-radius: 12px;
  padding: 24px 28px;
  display: flex;
  align-items: baseline;
  gap: 16px;
}

.stat-number {
  font-family: var(--font-display);
  font-size: 2.4rem;
  font-weight: 700;
  color: var(--accent-bright);
  line-height: 1;
}

.stat-label {
  font-size: 0.95rem;
  color: var(--fg-muted);
}

.hero-domains {
  display: flex;
  flex-wrap: wrap;
  gap: 10px;
  padding-top: 12px;
  border-top: 1px solid var(--border);
}

.domain-tag {
  font-family: var(--font-display);
  font-size: 13px;
  font-weight: 500;
  color: var(--fg-muted);
  background: var(--bg-elevated);
  border: 1px solid var(--border);
  padding: 6px 14px;
  border-radius: 6px;
}

/* ─── MECHANISM ─── */
.mechanism {
  padding: 100px 0;
  background: var(--bg-elevated);
}

.section-heading {
  font-size: clamp(1.8rem, 3.5vw, 2.4rem);
  margin-bottom: 56px;
  text-align: center;
}

.mechanism-grid {
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  gap: 24px;
}

.mechanism-step {
  background: var(--bg-card);
  border: 1px solid var(--border);
  border-radius: 12px;
  padding: 32px 24px;
}

.step-number {
  font-family: var(--font-display);
  font-size: 2rem;
  font-weight: 700;
  color: var(--accent);
  opacity: 0.4;
  margin-bottom: 16px;
}

.mechanism-step h3 {
  font-size: 1.1rem;
  margin-bottom: 12px;
  color: var(--fg);
}

.mechanism-step p {
  font-size: 0.92rem;
  color: var(--fg-muted);
  line-height: 1.65;
}

/* ─── PIPELINE ─── */
.pipeline {
  padding: 100px 0;
}

.pipeline-split {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 60px;
  align-items: center;
}

.pipeline-text h2 {
  font-size: clamp(1.6rem, 3vw, 2.2rem);
  margin-bottom: 24px;
}

.pipeline-text p {
  color: var(--fg-muted);
  margin-bottom: 16px;
  font-size: 0.98rem;
}

.pipeline-visual {
  padding: 32px;
  background: var(--bg-card);
  border: 1px solid var(--border);
  border-radius: 12px;
}

.pipeline-bar {
  display: flex;
  border-radius: 8px;
  overflow: hidden;
  height: 56px;
  margin-bottom: 16px;
}

.bar-segment {
  display: flex;
  align-items: center;
  justify-content: center;
  transition: flex 0.3s;
}

.bar-segment span {
  font-family: var(--font-display);
  font-size: 10px;
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.05em;
  color: rgba(255,255,255,0.9);
}

.seg-hema { background: var(--hema); }
.seg-card { background: var(--card); }
.seg-hepa { background: var(--hepa); }
.seg-hepa span { color: rgba(0,0,0,0.7); }
.seg-pulm { background: var(--pulm); }
.seg-pulm span { color: rgba(0,0,0,0.7); }
.seg-neur { background: var(--neur); }
.seg-onco { background: var(--onco); }
.seg-hcp { background: var(--hcp); }

.pipeline-meta {
  font-family: var(--font-display);
  font-size: 0.85rem;
  color: var(--fg-muted);
  text-align: center;
}

/* ─── MODEL ─── */
.model {
  padding: 100px 0;
  background: var(--bg-elevated);
}

.model-columns {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 40px;
  max-width: 800px;
  margin: 0 auto;
}

.model-col {
  background: var(--bg-card);
  border: 1px solid var(--border);
  border-radius: 12px;
  padding: 36px 32px;
}

.model-col h3 {
  font-size: 1.2rem;
  margin-bottom: 20px;
}

.model-is h3 { color: var(--accent-bright); }
.model-not h3 { color: var(--fg-muted); }

.model-col ul {
  list-style: none;
}

.model-col li {
  font-size: 0.95rem;
  color: var(--fg-muted);
  padding: 8px 0;
  border-bottom: 1px solid var(--border);
}

.model-col li:last-child { border-bottom: none; }

.model-is li::before {
  content: '\2713 ';
  color: var(--accent-bright);
  font-weight: 600;
  margin-right: 8px;
}

.model-not li::before {
  content: '\2717 ';
  color: #ef4444;
  font-weight: 600;
  margin-right: 8px;
}

/* ─── CLOSING ─── */
.closing {
  padding: 120px 0;
  text-align: center;
}

.closing-quote {
  font-family: var(--font-display);
  font-size: clamp(1.2rem, 2.5vw, 1.6rem);
  font-weight: 500;
  color: var(--fg);
  max-width: 780px;
  margin: 0 auto 32px;
  border: none;
  font-style: normal;
  line-height: 1.55;
}

.closing-mission {
  font-family: var(--font-display);
  font-size: clamp(1.6rem, 3vw, 2.2rem);
  font-weight: 700;
  color: var(--accent-bright);
}

/* ─── FOOTER ─── */
.site-footer {
  padding: 40px 0;
  border-top: 1px solid var(--border);
}

.footer-content {
  display: flex;
  align-items: center;
  justify-content: space-between;
}

.footer-brand {
  font-family: var(--font-display);
  font-size: 1rem;
  font-weight: 600;
  color: var(--fg);
}

.footer-info, .footer-contact {
  font-size: 0.85rem;
  color: var(--fg-muted);
}

/* ─── RESPONSIVE ─── */
@media (max-width: 768px) {
  .hero { padding: 60px 20px 40px; }

  .hero-grid {
    grid-template-columns: 1fr;
    gap: 40px;
  }

  .hero-stats {
    flex-direction: row;
    flex-wrap: wrap;
  }

  .stat-card {
    flex: 1;
    min-width: 140px;
    flex-direction: column;
    gap: 4px;
    padding: 16px;
    text-align: center;
  }

  .mechanism-grid {
    grid-template-columns: 1fr;
    gap: 16px;
  }

  .pipeline-split {
    grid-template-columns: 1fr;
    gap: 32px;
  }

  .model-columns {
    grid-template-columns: 1fr;
    gap: 20px;
  }

  .bar-segment span {
    font-size: 8px;
  }

  .footer-content {
    flex-direction: column;
    gap: 8px;
    text-align: center;
  }
}